摘要
目的 :探讨鼻泪管黏膜相关淋巴组织的组织学特点 ,初步揭示泪道炎症不易治愈的局部原因。方法 :通过常规苏木精 伊红染色 ,利用图像分析仪对兔鼻泪管、鼻腔、咽腔和气管黏膜中的淋巴滤泡发育情况 ,高内皮静脉 (HEV)的分布情况及其周围淋巴细胞浸润的密度进行分析。结果 :鼻泪管黏膜组织中淋巴滤泡和HEV的数量及其周围淋巴细胞浸润的程度均低于鼻腔、咽腔和气管黏膜 (P <0 .0 1)。结论 :正常情况下鼻泪管黏膜的局部免疫反应程度低于鼻腔、咽腔和气管黏膜 ,其黏膜下淋巴组织欠发达可能是泪道炎症不易治愈的主要原因。
Objective:To investigate the features of nasolacrimal duct MALT (mucosa-associated lymphoid tissue), and to explore the aetiology of chronic dacryocystitis.Method:The mucous of nasolacrimal duct, nasal cavity, pharyngeal and trachea of 20 rabbits were studied, and the lymphoid tissue and HEV of them were compared.Result:The number of lymphoid follicle and HEV in nasolacrimal duct epidermis were less than that in nasal cavity, pharyngeal and trachea(P< 0.01 ).Conclusion:In normal condition the immune response of nasalacrimal duct membranae is lower than other mucosa of head-neck.
出处
《临床耳鼻咽喉科杂志》
CAS
CSCD
北大核心
2004年第8期488-489,共2页
Journal of Clinical Otorhinolaryngology
基金
广东省医学科研基金资助项目 (No :A2 0 0 4 35 5 )
暨南大学医学院科研基金资助项目 (No :2 0 0 30 8)
关键词
鼻泪管
黏膜相关淋巴组织
组织学
Nasolacrimal duct
Mucosa-associated lymphoid tissue
Histology
