摘要
随着在细胞分子水平上对疾病发病机制认识的深入,基因治疗已成为目前医学分子生物学最重要的研究领域之一。基因治疗过程中基因转移技术起着关键作用,携带目的基因的载体有待进一步开发和改进。在基因治疗过程中,需要进行基因监测,基因显像是其最有效的方法。将基因治疗与靶向核素治疗相结合,即“基因靶向核素治疗”为肿瘤基因治疗开辟了一条崭新的途径。
With deeper cognition about mechanisms of disease at the cellular and molecular level, gene therapy has become one of the most important research fields in medical molecular biology at present. Gene transfer technology plays an important role during the course of gene therapy, and further improvement should be made about vectors carrying target gene sequences. Also, gene survey is needed during gene thera-py, and gene imaging is the most effective method. The combination of gene therapy and targeted radiothera-py, that is,'Genetic Radioisotope Targeting Therapy', will be a novel approach to tumor gene therapy.
出处
《国外医学（放射医学核医学分册）》
2004年第4期145-149,共5页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词
基因转移载体
基因显像
基因治疗
基因靶向核素治疗
gene transfer vector
gene imaging
gene therapy
genetic radioisotope targeting therapy
