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血红素氧合酶-1在肾脏疾病中的保护作用研究进展 被引量：1

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摘要 诱导型血红素氧合酶—血红素氧合酶 1(HO 1)是机体最重要的内源性保护物质之一 ,广泛参与组织细胞的抗氧化应激损伤 ,对多种病理状态造成的肾损伤起着重要的保护作用。
作者 张英 林燕 李著华
机构地区 [
出处 《国外医学（泌尿系统分册）》 2004年第5期715-718,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 肾疾病 血红素氧化酶(脱环)
分类号 R692 [医药卫生—泌尿科学]
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参考文献19

  • 1Agarwal A,Nick HS.Renal response to tissue injury:Lessons from heme oxygenase-1 GeneAblation and expression.J Am Soc Nephrol,2000,11(5):965-973.
  • 2Hill-Kapturczak N,Chang SH,Agarwal A.Heme oxygenase and the kidney.DNA Cell Biol,2002,21(4):307-321.
  • 3Yamada N,Yamaya M,Okinaga S,et al.Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema.Am J Hum Genet,2000,66(1):187-195.
  • 4Alam J,Camhi S,Choi AMK.Identification of a second 5'distal region that functions as a basal and inducer-dependent transcriptional enhancer of the mouse heme oxygenase-1 gene.J Biol Chem,1995,270(20):11977-11984.
  • 5He CH,Gong P,Hu B,et al.Identification of activating transcription factor 4 (ATF4)as a Nrf2 interacting protein:Implication for heme oxygenase-1 gene regulation.J Biol Chem,2001,276(24):20858-20865.
  • 6Chen YH,Lin SJ,Lin MW,et al.Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients.Hum Genet,2002,111(1):1-8.
  • 7Nath KA,Haggard JJ,Croatt AJ,et al.The indispensability of heme oxygenase-1(HO-1) in protecting against acute heme protein-induced toxicity in vivo.Am J Pathol,2000,156(5):1527-1535.
  • 8Agarwal A,Balla J,Alam J,et al.Induction of heme oxygenase in toxic renal injury:A protective role in cisplatin nephrotoxicity in the rat.Kidney Int,1995,48(4):1298-1307.
  • 9Shiraishi F,Curtis LM,Truong L,et al.Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis.Am J Physiol Renal Physiol,2000,27(5):F726-F736.
  • 10Schaaf GJ,Maas RF,de Groene EM,et al.Management of oxidative stress by heme oxygenase-1 in cisplatin-induced toxicity in renal tubular cells.Free Radic Res,2002,36(8):835-843.

同被引文献14

  • 1袁媛,龙村,关彬,史世勇,温福兴,张燕婉.褪黑素对鼠心肌缺血再灌注损伤的保护作用[J].中华实验外科杂志,2005,22(3):331-332. 被引量：2
  • 2Hong SY, Yang DH, Hwang KY, etal. Associations between la boratory parameters and outcome of paraquat poisoning [J]. Toxicol Lett,2000,118(122) : 53-59.
  • 3Shihab FS, Bennett WM, Tanner AM. AngiotensinlI blockade decreases TGF-B1 and matrix proteins in cyclosporine nephropathy [J]. Kidney Int, 1997,52 : 660-673.
  • 4Soslow RA, Dannenberg AJ, Rush D, etal. Cox-2 is expressed in human pulmonary, colonic, and mammary tumors [J]. Cancer, 2000,89(12) :2637-2645.
  • 5Kvtnoy IM. Extrapineal melatonin;location and role within diffuse neuroendocrine system[J]. H istochem J, 1999,31 (1) : 1- 12.
  • 6Sener G, Sehirli AO, Altunbas HZ, et al. Melatonin protects against gentamicin-induced nephrotoxicity in rats[J]. Pineal Res, 2002,32(4):231 -236.
  • 7Costantini P, Petronilli V, Colonna R, etal . On the effect of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin a sensitive permeability transition poresynergistically with nitricoxide [J]. Toxicology, 1995, 99 ( 1-2 ): 77-88.
  • 8Hill-Kapturczak N, Chang Sh, Agarwal A. Heme oxygenase and the kidney[J]. DNA Cell Biol, 2002,21(4) : 307-321.
  • 9Tomita M, Okuyama T, Katsuyama H, et al. Paraquat-induced gene expression in rat kidney [J]. Arch Toxicol, 2006, (10) 687-693.
  • 10Morse D, Choi AM. Heine oxygenase-1 : the "emerging molecule" has arrived[J]. Am J Respir Cell Mol Biol,2002,27(1):8-16.

引证文献1

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国外医学（泌尿系统分册）
2004年 第5期

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