摘要
①目的 探讨山东沿海居民慢性淋巴细胞性甲状腺炎 (CLT)患病情况及影响因素。②方法 采取分层整群抽样法 ,对山东沿海地区烟台、威海、日照和青岛居民CLT患病情况及其尿碘水平进行调查。③结果山东沿海地区CTL患病率为 0 .91 % ;CLT分布呈区域性 ,离海越近 ,居民尿碘排泄率越高 ,CLT患病率也越高(χ2 =4 .1 6～ 7.95 ,P <0 .0 5、0 .0 1 ) ;尿碘中位数超过 30 0 μg/L时 ,CLT患病率明显升高 (χ2 =4 .2 3～ 36 .94 ,P <0 .0 5、0 .0 1 )。尿碘水平与抗甲状腺球蛋白抗体 (TGAb)、抗甲状腺过氧化物酶抗体 (TPOAb)有关 (P <0 .0 5、0 .0 1 )。④结论 沿海地区碘摄入过多可能诱发CLT发生和发展 ,沿海居民尿碘浓度应控制在 30 0 μg/L以下。
Objective To survey the prevalence and related factors of chronic lymphocyte thyroiditis(CLT) in people residing in the coastal areas in Shandong province. Methods The CLT prevalence and urine iodine level of the residents in Shandong coastal areas, including Yantai, Weihai, Rizhao and Qingdao, were investigated with random layer sampling method. Results The prevalence of CLT in the areas was 0.91% with regional differences. The closer to the coast, the higher the prevalence rate of CLT( χ 2=4.16-7.95;P <0.05,0.01).When the urine iodine median was over 300 μg/ L, the CLT morbidity rate went up obviously ( χ 2=4.23-36.94;P <0.05,0.01). The urine iodine was positively correlated with TGAb, TPOAb ( P < 0.05 ,0.01). Conclusion\ Excessive intake of iodine may induce the genesis and development of CLT. The urine iodine of residents in the coastal areas should be controlled to less than 300 μg/ L .
出处
《青岛大学医学院学报》
CAS
2004年第3期192-194,共3页
Acta Academiae Medicinae Qingdao Universitatis
