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快速老化痴呆模型小白鼠SAMP8和SAMP10老化特征及其相关研究进展 被引量:19

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出处 《实验动物科学与管理》 2004年第3期51-57,共7页 Laboratory Animal Science & Administration
基金 天津市自然科学基金资助 (No.0 336 0 6 811)
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  • 1Takeda T, Matsushita T, Kurozumi M et al. Pathobiology of the senescence-accelerated mouse (SAM). Exp Gerontol, 1997, 32(1 ~ 2): 117 ~ 127.
  • 2Takeda T, Hosokawa M, Higuchi K. Senescenceaccelerated mouse (SAM): a novel murine model of senescence. Exp Gerontol, 1997,32(1 ~ 2): 105 ~ 109.
  • 3Takeda T. Senescence-accelerated mouse (SAM): a biogerontological resource in aging research. Neurobiol Aging, 1999,20(2): 105~110.
  • 4Shimada A, Ohta A, Akiguchi I et al. Inbred SAM-P/10 as a mouse model of spontaneous, inherited brain atrophy. J Neuropathol Exp Neurol, 1992, 51(4) :440 ~ 450.
  • 5Shimada A, Hosokawa M, Ohta A et al. Localization of atrophy - prone areas in the aging mouse brain: comparison between the brain atrophy model SAM - P/10 and thc normal control SAM-R/1. Neuroscience, 1994,59(4) :859 ~ 869.
  • 6Miyamoto M. Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP 10.Exp Gerontol, 1997,32( 1 ~ 2):139~ 148.
  • 7Nomura Y, Okuma Y. Age-related defects in lifespan and learning ability in SAMP8 mice. Neurobiol Aging, 1999,20(2): 111 ~ 115.
  • 8Yagi H, Akiguchi I, Ohta A et al. Spontaneous and artificial lesions of magnocellular reticular formation of brainstem deteriorate avoidance learning in senescenceaccelerated mouse SAM. Brain Res, 1998,791 (1 ~ 2): 90~ 98.
  • 9Amano T, Nakanishi H, Oka M et al. Increased expression of cathepsins E and D in reactive microglial cells associated with spongiform degeneration in the brain stem of senescence-accelerated mouse. Exp Neurol, 1995,136(2):171 ~ 182.
  • 10杉山博.快速老化小白鼠(SAM)—作为痴呆动物的可能性[J].日本医学之步,1988,146(9):225-227.

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