摘要
本文探讨了五子衍宗丸对小鼠免疫功能的影响。结果表明,五子衍宗丸对正常小鼠外周血白细胞总数及酸性非特异性脂酶阳性淋巴细胞百分率无明显影响(P>0.05),对正常小鼠脾细胞产生抗体功能亦无明显影响(P>0.05),但对正常小鼠及免疫受抑小鼠的单核吞噬细胞功能有明显的激活增强作用(P<0.01),对免疫受抑小鼠外周血白细胞总数及酸性非特异性脂酶阳性淋巴细胞百分率的减少有防治作用(P<0.01),对免疫受抑小鼠脾细胞产生抗体功能有明显的促进作用。结果提示,五子衍宗丸对正常小鼠的部分非特异性免疫功能有一定的增强作用,而对免疫受抑小鼠的非特异性免疫功能及特异性免疫功能(包括细胞免疫和体液丸疫)均有明显的增强作用。
The effects of Wuzi Yanzong Wan on the immune functions in mice were investigated. The results showed that the preparation restored immune function of immunosuppressive mice, e.g., increasing the number of peripheral white blood cells and the percentage of acid nonspecific esterase positive lymphocytes, promoting the antibody-producing function of spleen cells and the phagocytosis of macrophages. It was shown that Wuzi Yanzong Wan can enhance both nonspecific and specific immune functions (including cellular and humoral immunity) of immunosuppressive mice.
关键词
五子补肾丸
药理学
肾虚
中医药疗法
细胞免疫
WUZI BUSHEN WAN/pharm. WUZI BUSHEN WAN/ther.use KIDNEY ASTHENIA/TCM ther. IMMUNITY, NATURAL/drug eff. IMMUNITY, CELLULAR/drug eff. ANTIBODY FORMATION/drug eff.
