摘要
探讨手术全切或大部切除肿瘤后 ,球囊置入3 2 P内放疗治疗脑胶质瘤的疗效及临床价值。对 2 18例脑胶质瘤患者行手术切除或大部切除后 ,瘤腔内置硅胶球囊外接注药泵埋入皮下。手术后即将3 2 P9mci注入硅胶球囊 ,以后每 2个月更换一次 (通过穿刺注药泵更换 )。随访观察存活 1年以上者 166例 ,占 76 1% ( 166/2 18) ,2年以上者 10 9例 ,占 5 0 0 % ( 10 9/2 18) ,3年以上者 89例 ,占 40 8% ( 89/2 18) ;5年以上者 61例 ,占 2 7 9% ( 61/2 18)。其中生存 5年以上者 ,有 3 4例取硅胶球时 ,球囊周围多点取病理 ,未见肿瘤细胞。手术加球囊置入3 2 P内放疗生存时间长 ,并发症少 ,是治疗脑胶质瘤的理想方法 。
The objective is to explore the effect and clinical value of inter-radiotherapy of 32P put into sacculus in gliomas.Two hundred and eighteen cases of glioma were resected completely or in large part.The sacculus were put into tumor cavity and combined with injection pump buried in infra-epicranium,and 9 mci 32P was injected into the sacculus as soon as the operation had been completed. 32P was changed every 2 months by puncturing injection pump.In all patients who were followed up,the 1-,2-,3- and 5-year survived cases were 166,109,89 and 61 cases and their survival rates were 76.6%,50.0%,40.8% and 27.9%.Tumor cells were not found in the brain tissues near the sacculus by patheology when the sacculus were put out in 34 over 5-year survival cases.Inconclusion,treatment of operation plus inter-radiotherapy in gliomas can improve the survival rates and reduce complications.This therapy is a good method for curing gliomas,and it needs to be further discussed.
出处
《肿瘤防治杂志》
2004年第8期864-865,共2页
China Journal of Cancer Prevention and Treatment
基金
山东省卫生厅课题 ( 1990 -0 11)
