摘要
不同动物的剂量换算 ,在基础药理和I期临床研究中具有现实指导意义 ,本文将动物体型系数及其标准体重引入公式 ,通过查表 ,可方便地估算出不同动物间和动物与人体间的等效剂量。
In order to obtain equivalent dose, a dose conversion was important among different animals and healthy volunteers in preclinical pharmacology and I phase clinical trials. Body coefficient and standard weight were introduced into the formula to estimate the equivalent dose in this paper.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2004年第9期1069-1072,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
剂量换算
等效剂量
Ⅰ期临床试验
健康志愿者
dose conversion
I phase clinical trial
human equivalent dose
healthy volunteers
