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高血压患者血清SOD、LPO、GSH-PX含量的变化及其临床意义 被引量:21

Clinical Significance of Changes of Serum SOD, LPO and GSH-PX Levels in Patients with Hypertension
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摘要 目的 :探讨了高血压患者血清中SOD、LPO、GSH -PX含量的变化。方法 :分别应用放射免疫分析和生化法对 5 5例高血压患者进行了SOD、LPO、GSH -PX水平的检测 ,并与 38名正常健康人作比较。结果 :高血压患者血清中SOD、GSH -PX水平明显低于正常人组 (P <0 .0 1 ) ,而LPO水平则明显高于正常人组 (P <0 .0 1 )。结论 :血清SOD、LPO、GSH Objective To explore the changes of serum SOD、 LPO and GSH-PX levels in patients with essential hypertension. Methods Levels of serum SOD were detected with RIA and LPO/GSH-PX levels with biochemical methods in 55 cases of essential hypertension and 38 controls. Results In the patients, the SOD、 GSH-PX levels were singificantly lower and LPO levels were significantly higher than those in controls ( P <0.01). Conclusion The levels of serum SOD、 LPO、 GSH-PX were closely correlated to the severity of the hypertension.
出处 《放射免疫学杂志》 CAS 2004年第4期261-262,共2页 Journal of Radioimmanology
关键词 高血压 血清 SOD LPO GSH—PX 含量 超氧化物歧化酶 过氧化脂质 谷胱甘肽过氧化物酶 hypertension, superoxide dismutase(SOD), lipoper oxides(LPO), glutathione peroxide(GSH-PX)
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