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生长抑素和生长激素联合应用治疗重症急性胰腺炎临床观察 被引量:6

Clinical observation on treatment of severe acute pancreatitis with combination of somatostatin and growth hormone
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摘要 目的探讨临床联合应用八肽生长抑素善宁+生长激素思增治疗重症急性胰腺炎是否优于临床单用善宁.方法回顾性分析1997年1月~2003年12月单用八肽生长抑素-善宁组(32例)与联合应用善宁+思增组(37例)治疗重症急性胰腺炎的临床结果,比较两组病人平均住院天数(47VS33)、血浆白蛋白转归(2.9VS3.5)、严重并发症发生率(20VS12).结果联合应用八肽生长抑素善宁+生长激素思增治疗重症急性胰腺炎效果明显优于单用善宁,两组间病人平均住院天数、血浆白蛋白回复时间、严重并发症发生率显著低于对照组(P<0.05),两组间具有显著差别(P<0.05).结论临床联合应用八肽生长抑素善宁+生长激素思增能显著缩短患者总住院日及血浆白蛋白回复时间,减少严重并发症发生率,具有较好疗效. Objective: To evaluate the curative effect of combination treatment with somatostatin (ST) and growth hormone (GH) in severe acute pancreatitis (SAP). Methods: Retrospectively analysed the therapeutic results of somatostatin/combination of somatostatin and growth hormone on severe acute pancreatitis between the phase of 1997.01~2003.12. Results: The effect of combination of somatostatin and growth hormone on SAP was significantly superior to somatostatin singly. The former significantly reduced the hospitalized days (47/33), shortened the recovering period of Alb (2.9/3.5), and decreased the rates of complications (20/12). The hopitalized days, the recovering period of Alb and the rats of complications were significantly different in the two groups. Conclusion: The combination of somatostatin and growth hormone on SAP significantly reduces the hospitalized days, shortens the recovering period of albumin, decreases the rates of complications and improves the prognosis.
作者 胡雄 廖健
出处 《中国现代医学杂志》 CAS CSCD 2004年第18期127-128,131,共3页 China Journal of Modern Medicine
关键词 重症胰腺炎/急性 生长抑素 生长激素 severe acute pancreatictis (SAP) somatostatin growth hormone (GH)
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