摘要
目的 观测利多卡因能否减轻肝癌TACE术引起的疼痛 ,以保证肝动脉栓塞治疗的顺利进行。方法 114例次肝癌患者行TACE术 ,随机分组 :6 8例次在注入栓塞前一次性注入 2 %利多卡因 10 0mg ,另 4 6例次为对照组。 结果 利多卡因组疼痛的发生率及平均止痛药物剂量分别为 19.1%和 ( 16 .17± 4 .96 )mg ,对照组疼痛发生率和平均止痛药物剂量为 6 3.0 4 %和( 93.4 7± 14 .0 4 )mg。结论 栓塞前注入利多卡因可明显减轻术后疼痛的发生和程度以及减少止痛药物的用量、促进患者的恢复 。
OBJECTIVE Application of lidocaine for relief of pain during transarterial chemoembolization to guarantee arterial chemoembolization carrying out smoothly. METHOD In a prospective trial, 114congsecutive patients with HCC who underwent TACE were divided into two groups: those who received a lidocaine bolus intraarterially immediately prior to TACE(group A, n =68)and those who did not received lidocaine(group B, n =46).RESULTS The incidence of post procedural pain and the mean dose of analgesic used after the procedure in group A were 19.1% and 16.17mg, those in group B ( P =0.001<0.005)were 63.04% and 93.47mg . CONCLUSION Intra arterial administration of lidocaine prior to TACE is much more effective to reduce the severity of pain, dosage of analgesics and make the patients get quick recovery, which guarantees the TACE to obtain the anticipated results.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2003年第6期519-521,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
肝肿瘤
动脉栓塞化疗
疼痛
利多卡因
liver neoplasms
transarterial chemoembolization
pain
lidocaine
