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妊娠期肝内胆汁淤积症145例临床分析

PREGNANCY WITH INTRAHEPATIC CHOLESTASIS: A REPORT OF 145 CASES
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摘要 目的:探讨妊娠期肝内胆汁淤积症(ICP)诊断及分娩方式。方法:回顾性分析145例ICP病人临床资料,对其诊断、治疗、分娩方式、新生儿预后进行分析和总结。结果:皮肤瘙痒者占77.24%,黄疸发生率13.79%,胆酸及肝酶升高者达100%,早产发生率15.17%,胎儿窘迫发生率4.83%,剖宫产率67.59%(社会因素为剖宫产指征占22.45%),经阴道分娩人数占32.14%,产后出血8.28%,元围生儿死亡。结论:胆酸升高是诊断ICP唯一不可缺少的指标,且为早期诊断指标;ICP若能得到早诊断、早治疗,即可降低对胎儿的不良影响;产时加强监护,阴道分娩也安全。 Objective: To investigate diagnostic methods and labor ways for pregnant women with intrahepatic cholesta sis. Method:Data including diagnosis, treatment, labor way and prognosis in 145 pregnant women were analysed. Results:Of the 145 patients, 77.2% complained of pruritus and 13.79% had jaundice; 100% patients had cholic acid and hepatic enzyme increase, The incidence for premature labor was 15.17% , fetal asphyxia 4.83% , hysterotokotomy 67.59% , postpartum hemorrhage 8.28% and vaginal labor 32.14% . There was no case of perinatal period death. Conclusion: Increase of cholic acid is a early and important sign for diagnosis of pregnancy with intrahepatic cholestasis. It is safe by vaginal labor if early intervention methods are taken to reduce risk factors to fetus.
出处 《九江医学》 2004年第2期71-73,共3页 Jiujiang Medical Journal
关键词 妊娠并发症 胆汁淤积 肝内 产科 pregnancy complication cholestasis,intrahepatic obstetrics
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