摘要
目的 :研究愈创膜抗炎镇痛作用及其皮肤急性毒性。方法 :采用二甲苯致炎法、角叉菜胶致炎法和醋酸扭体法 ,观察愈创膜的抗炎镇痛作用 ;取健康家兔脱毛 ,敷贴给予愈创膜 ,观察膜剂对皮肤的急性毒性。结果 :愈创膜对二甲苯所致小鼠耳廓肿胀、角叉菜胶所致大鼠足跖肿胀及小鼠醋酸扭体反应有明显的抑制作用 ;对完整皮肤和破损皮肤均未见明显的毒性作用。结论 :愈创膜具有显著的抗炎镇痛作用 。
Objective:Study the anti inflammatory and analgesic action of Yuchuan film and its acute toxicity of skin. Method:Take the methods of inflammation induced by xyleneand carrageenin,and the acetic acid body twisting method,observe the anti infalammatory and analgesic action of Yuchuan film.Take healthy rabbits for trichomadesis,apply Yuchuan film,then observe the acute toxicity of the film on the skin.Result:The Yuchuan film has apparent inhibition on the mice auricle swelling induced by xylene,rats feet swelling induced by carrgaeenin and acetic acid twisting reaction,but without obvious toxicity on the healthy and injured skin. Conclusion:Yuchuan film has marked anti inflammatory and analgesic action,and is an external pharmaceutics with good safety.
出处
《浙江中医学院学报》
2004年第5期63-64,共2页
Journal of Zhejiang College of Traditional Chinese Medicine
基金
国家中医药管理局科研基金课题 (编号 97Y2 0 5)
