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不同刺激模式前庭诱发肌源性电位的反应特性 被引量:41

Characteristics of the response of vestibular evoked myogenic potentials to different stimulus modes
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摘要 目的 前庭诱发的肌源性电位(vestibular evoked myogenic potential,VEMP)可用于评价球囊功能及其对称性,比较3种刺激模式VEMP的振幅与潜伏期,希望得出适合临床应用的方法。方法 测量21名健康成人3种刺激模式(双侧短声、1侧短声和1侧短声对侧白噪声)的VEMP的潜伏期、振幅,计算出3种情况下的振幅及潜伏期的均值、双侧振幅比值、双侧振幅不对称性。结果 3种刺激模式刺激侧振幅与潜伏期无明显差异,但1侧短声刺激对侧振幅低于刺激侧,潜伏期比刺激侧长2-3 ms。双侧短声刺激p13波和n23波出现率为100%,1侧短声对侧白噪声刺激p13和n23出现率最低,无特别应用的意义。3种刺激方式VEMPs振幅变化较大。结论 VEMP是一种稳定的肌源性电位,双侧短声刺激和1侧短声刺激都不失为较好的刺激方法,双侧给声对双侧听力正常者较为适宜。应用双侧VEMP的振幅比值和对称性,判断双侧球囊的功能。 Objective Vestibular evoked myogenic potential (VEMP) has been utilized in clinic to test the function of saccule. In the present study, 3 stimulus modes were applied to 21 normal adults and intended to draw in a clinical test protocol. Methods The normal latency and amplitude of VEMPs of 21 normal subjects were recorded and the ratio of bilateral amplitudes and asymmetry were calculated. Results The response to binaural clicks were similar to the response of the monoaural clicks. The interindividual variation in amplitude were large , but the latency varied little. Conclusions VEMPs is a stable myogenic potentials. Monoaural and binaural clicks stimulus can be used in clinical practice. The latter is appropriate for nomal hearing subjects. Amplitude measurement is probable to evaluate the asymmetry of bilateral saccular function and may reveal saccule lesion.
出处 《中华耳鼻咽喉科杂志》 CSCD 北大核心 2004年第8期483-485,共3页 Chinese Journal of Otorhinolaryngology
关键词 肌源性电位 反应特性 前庭诱发 球囊功能 刺激模式 诱发电位 Evoked potentials Acoustic stimulation Saccule and utricle
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