摘要
目的观察大鼠浅Ⅱ度烫伤创面即刻施行冷疗后,在湿热环境下皮肤温度的变化。同时,评价冷疗敷料方法的降温效果。方法24只Wistar大鼠,随机分成4组,即常温常湿对照组(常对组)、常温常湿冷疗组(常冷组)、湿热对照组(高对组)和湿热冷疗组(高冷组),每组6只。制作浅Ⅱ度烫伤模型后分别采取不同的干预条件,常温组的实验环境条件为干球温度(Tdb)(26.33±1.29)℃、相对湿度(rh)(71.05±4.57)%,湿热组的实验环境条件为Tdb(35.33±0.35)℃,rh(70.81±1.38)%,对照组不给予冷疗降温,冷疗组给予腹部冷疗敷料降温,暴露时间均为125 min。监测皮肤温度(Ts),烫伤5 min 后每20 min记录1次。结果4组组内7个时间水平之间、不同时间水平组间以及不同组间比较,湿热环境使Ts升高(P<0.001),冷疗使Ts降低(P<0.001),且时间与环境温度(P≤0.002)、时间与冷疗(P<0.05)、时间、环境温度与冷疗对Ts变化影响有交互作用(P<0.05)。常温组冷疗前后Ts降低了(1.92±2.13)℃,湿热组Ts降低了(2.36±1.03)℃。结论在湿热环境下,腹部冷疗敷料有效降低了大鼠创面皮肤温度,阻止了热损伤的进程和创面余热的不良作用。
Objective To observe the changes in skin temperature after cooling therapy immediate following superficial second-degree scald injury in Wistar rats in a hot and humid environment, and evaluate the effect of the dressing materials for the cooling therapy. Methods Twenty-four Wistar rats were randomly divided into normal temperature control (NTC), normal temperature cooling therapy (NCT), hot and humid control (HHC), and hot and humid cooling therapy (HCT) groups (n=6). Different interventions were applied to the scalded rats: dry bulb temperature (Tdb) of 26.33±1.29 ℃ with a relative humidity (rh) of 71.05%±4.57% for the two normal temperature groups, and Tdb 35.33±0.35 ℃ with rh of 70.81%±1.38% for the two hot and humid environment groups. The dressing materials for the cooling therapy were applied to the two cooling therapy groups but not for the two control groups. The exposure time for the therapy was 125 min, and the skin temperature was measured every 20 min, starting from 5 min after the scald. Results The skin temperature rose in hot and humid environment and decreased when cold therapy was applied (P<0.001). Interactions were found between the exposure time and environ- mental temperature (P≤0.002), between the exposure time and cooling therapy (P<0.05), and between these 3 factors (P<0.05) to influence the skin temperature, which was 1.92±2.13 ℃ lower in NCT group than in NTC group, and 2.36±1.03 ℃ lower in HCT group than in HHC group. Conclusion The dressing materials for cooling therapy effectively reduce the skin temperature at the site of the scald injury to prevent the progression of heat-induced injury and the unfavorable effects of the heat remaining on the scalded skin.
出处
《第一军医大学学报》
CSCD
北大核心
2004年第10期1120-1122,共3页
Journal of First Military Medical University
基金
军队"十五"重点攻关课题(01Z100)~~
关键词
湿热环境
干球温度
相对湿度
烫伤
冷却疗法
皮肤温度
hot and humid environment
dry bulb temperatuve
relatire humidity, scald injury
cooling therapy
skin temperature
