摘要
目的探讨糖尿病足发病的危险因素。方法观察78例糖尿病足和110例糖尿病足患者的一般资料、肝肾功能、血糖、血脂等以及糖尿病各种慢性并发症,经非条件Logistic回归分析筛选其危险因素。结果年龄(OR=1.0485,95%可信区间1.0187～1.0783)、职业(OR=0.5250,95%可信区间0.0534～1.1034)、餐后血糖(OR=1.1222,95%可信区间1.0432～1.2012)、糖化血红蛋白(OR=1.2333,95%可信区间1.0591～1.3715)、血纤维蛋白原(OR=2.0515,95%可信区间1.7287～2.3743)、糖尿病周围神经病变(OR=3.6305,95%可信区间2.9541～4.3114)、糖尿病周围血管病变(OR=2.5435,95%可信区间2.2395～2.8475)、糖尿病肾病(OR=1.5618,95%可信区间1.1935～1.9301)、糖尿病视网膜病变(OR=2.3521,95%可信区间1.7676～2.9366)等与糖尿病足发病有关,有统计学意义(P<0.05)。结论严格控制血糖、血粘度,积极治疗糖尿病各种慢性并发症能有效预防糖尿病足的发生。
Objective To study the risk factors for type 2 diabetics with foot gangrene. Methods The clinical data (including general data, liver function, renal function, lipid profile and the chronic diabetic complications, et al.) of 78 diabetics with and 110 patients without foot gangrene was reviewed. Data was analyzed by non-conditional logistic regression model. Results Age (OR=1.048 5,95%CI 1.018 7～1.078 3), profession (OR=0.525 0,95%CI 0.053 4～1.103 4), postprandial blood glucose (OR=1.122 2,95%CI 1.034 2～1.201 2), glycosylated hemoglobin (OR=1.233 3,95%CI 1.059 1～1.371 5), fibrinogen (OR=2.051 5,95%CI 1.728 7～2.374 3), diabetic neuropathy(OR=3.630 5,95%CI 2.954 1～4.311 4), diabetic peripheral vascular diseases (OR=2.543 5,95%CI 2.239 5～2.847 5), diabetic nephropathy (OR=1.561 8,95%CI1.193 5～1.930 1), as well as diabetic retinopathy (OR=2.352 1,95%CI 1.767 6～2.936 6 ) had significant relationship with diabetic foot (P<0.005). Conclusions The diabetic foot can be prevented by controlling blood glucose strictly and by treating the chronic diabetic complications.
出处
《中国慢性病预防与控制》
CAS
2004年第5期206-208,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
关键词
糖尿病足
危险因素
Diabetes foot
Risk factors
