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蛋白质分子印迹聚合物研究 被引量:4

STUDIES ON PROTEIN IMPRINTED POLYMERS
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摘要 Molecularly imprinted polymers (MIPs) were prepared by using acrylic derivatives as the functional monomers,ethylene glycol dimethacrylate (EDMA) as the cross-linker,bovine serum albumin (BSA) as the template.In order to obtain qualified protein imprinted polymers,detailed studies were carried out over the polymer compositions,chemical reagent adding sequence,UV radiation time and synthetic conditions.The experimental data showed that the BSA imprinted polymers,compared to their blank counterpart,exhibited desired adsorption affinities and selectivity to the BSA molecule,and the amounts of adsorption were obviously higher than that of the blank polymer. Molecularly imprinted polymers ( MIPs) were prepared by using acrylic derivatives as the functional monomers, ethylene glycol dimethacrylate ( EDMA) as the cross-linker, bovine serum albumin (BSA) as the template. In order to obtain qualified protein imprinted polymers, detailed studies were carried out over the polymer compositions, chemical reagent adding sequence, UV radiation time and synthetic conditions. The experimental data showed that the BSA imprinted polymers, compared to their blank counterpart, exhibited desired adsorption affinities and selectivity to the BSA molecule, and the amounts of adsorption were obviously higher than that of the blank polymer.
出处 《高分子学报》 SCIE CAS CSCD 北大核心 2004年第4期610-613,共4页 Acta Polymerica Sinica
基金 国家杰出青年科学基金 (基金号 2 0 0 2 5 617)资助项目
关键词 蛋白质 分子印迹聚合物 分子识别 人工受体 制备 molecular imprinting protein adsorption molecular recognition
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