摘要
目的研究中/长链甘油三酯(MCT/LCT)营养支持治疗儿科危重疾病的效果。方法 本研究为随机双盲、平行对照,需要肠外营养的50例ICU患儿分为2组,每组25例。根据营养配方选用的脂肪乳不同,分为对照组(长链甘油三酯,LCT)和MCT/LCT组,比较2周后两组的疗效和对细胞免疫、细胞外环境的影响。结果两组的营养治疗均有效、安全,但MCT/LCT组在淋巴细胞CD4/CD8和对细胞外环境的影响方面优于对照组(P<0.05)。结论 对于儿科ICU中危重患儿,中/长链甘油三酯更容易耐受,不会严重干扰细胞免疫和细胞外环境稳态。
Objective To investigate the effects of medium/long-chain triglycerides (MCT/LCT) emulsion in the treatment of children with serious diseases. Methods In a randomized and double-blind parallel controlled clinical study, 50 cases in children ICU in need of parental nutrition therapy, were divided into 2 groups (n=25). According to the triglycerides in nutrition menu, the groups were control group (long-chain triglycerides, LCT) and MCT/LCT group. During 2 weeks, the efficacy, and the effects of cellular immune and extracellular homeostatic were compared between 2 groups. Results The parental nutrition in 2 groups was efficient and safe. But the effect on immune and homeostatic in MCT/LCT was better than that of control (P<0.05). Conclusions MCT/LCT for children in ICU is more reliable and rarely intervenes cellular immune and extracellular homeostatic.
出处
《国际医药卫生导报》
2004年第20期58-59,共2页
International Medicine and Health Guidance News
