摘要
目的观察纳络酮抢救抗精神病药物急性中毒的疗效。方法回顾性对照研究门诊急诊抗精神病药物急性中毒患者使用纳络酮治疗与不使用纳络酮治疗,在疗效方面,主要是昏迷时间方面的差异。纳络酮治疗组52例,对照组56例。按GCS评分又将两组分为轻型、中型和重型,分别加以对照研究。结果纳络酮治疗组在轻、中、重各型与对照组的比较,其疗效(昏迷时间)均存在显著差异(P<0.01)。结论纳络酮对抢救抗精神病药物急性中毒的疗效显著,安全性好,值得推广使用。
objective To observe the efficacy of naloxone in the treatment of acute intoxication of anti-psychotic drugs. Methods 108 out-patient with acute anti-psychotic drug intoxication were reexamined in a retrospective study. All cases were divided into two groups,as one group treated with naloxone (n=52) and the other one not treated with naloxone (n=56). The therapeutic efficacy of two groups was compared. Results There were significant difference in improvement of coma between two groups (P<0.01). Conclusion It indicates that naloxone may be safe and effective in the treatment of acute intoxication of anti-psychotic drugs.
出处
《江西医药》
CAS
2004年第5期320-321,共2页
Jiangxi Medical Journal
