摘要
目的 探讨闭合性颅脑损伤患者血糖与白细胞介素 6的关系。方法 观察 4 0例闭合性颅脑损伤患者伤后第 1天血糖和白细胞介素 6的变化 ,并与 30例正常对照组患者比较。白细胞介素 6应用ELISA方法测定。结果 闭合性颅脑损伤患者血清白细胞介素 6明显高于正常对照组 (P <0 0 5 ) ,血清白细胞介素 6水平与血糖变化的相关系数为r=0 817(P <0 0 1)。结论 白细胞介素
Objective To investigate the relationship between serum level of blood glucose and interleukin 6 in patients with closed brain injury.Methods Forty patients with closed brain injury were selected.Venous blood sample was collected at the first day after injury.The changes of serum blood glucose and interleukin 6 levels were assessed,and the serum level of interleukin 6 determind with ELISA method.With the same way,serum interleukin 6 and blood glucose were measured in 30 normal healthy persons.Results The serum level of interleukin 6 was significantly higher in the patients with closed brain injury than in the controls (P<0.05).The correlation coefficient between the serum level of interleukin 6 and blood glucose was r=0.817(P<0.01).Conclusion Interleukin-6 is involved in the pathogenesis of hypeglycermia in patiens with acute closed brain injury.
出处
《中华急诊医学杂志》
CAS
CSCD
2004年第10期658-660,共3页
Chinese Journal of Emergency Medicine
基金
广东省重点科技攻关项目 ( 2KM0 480 2S)
