摘要
采用放射免疫法测定3s例男性肺心病急性发作期患者,30例缓解期患者和28名年龄相匹配的健康男性血清睾酮(T)、雌二醇(E_2)、黄体生成素(LH)、卵泡刺激素(FSH)、催乳素(PRL)含量,结果表明:男性肺心病患者血清 T、E_2、LH、FSH 低于正常人,与 PaO_2呈正相关;PRL 高于正常人,与 PaO_2呈负相关.提示缺氧是男性肺心病患者下丘脑-垂体-性腺轴功能紊乱的主要原因.
The sera of 35 male patients with the acute period of chronic cor pulmonale,30 male patients with the remission period of chronic cor pulmonale and 28 normals of similar ages and the same sex were analyzed by radio-immunoassay with 5 sexual hoemones:luteinic hormone (LH),follicle stimu- lating hormone (FSH),testosterone (T),estrogen (F_2) and prolactin (PRL).The result showed that LH,FSH,T and E_2 in the serum of the patients with chronic cor pulmonale were lower than those of the normals.Which was directly proportional to hypoxia.PRL and E_2/T higher than those of the con- tral,wich expressed a negative correlation with hypoxia.It was suggested that hypoxia be the main cause of the funmctional imblance of the hypothalmus-pitiutary sexual glandular axles in male patients with chroic cor pulmonale.
关键词
肺心病
诊断
性激素
男性
MeSH
pulmonary heart disease/DI
sex hormones/ME
male
