期刊文献+

不同b值在正常人脑组织磁共振扩散张量成像中的应用探讨 被引量:8

The application study of different b value in normal human brain diffusion tensor imaging
下载PDF
导出
摘要 目的获取正常人脑组织磁共振扩散张量图像,评价不同b值条件下的扩散张量图像改变。方法筛选28例正常(常规MR显示未见异常者)健康成年人,分别选取b=1000s/mm2,b=2000s/mm2和b=3000s/mm2同时进行磁共振扩散张量成像(DTI),应用Philips公司提供的分析软件分析扩散张量图。包括:各向同性表面扩散系数(ADCiso)图和各向异性图,测量不同b值时图像的信躁比(SNR)及灰白质对比度。结果随着b值的升高,各相同性图及ADCiso图均显示脑组织灰白质对比度增高,b=2000s/mm2组(或b=3000s/mm2组)与b=1000s/mm2组有显著差异(P<0.001),b=2000s/mm2组与b=3000s/mm2组无显著差异(P>0.05)。结论①b=1000s/mm2时,DTI图像质量最好,但脑组织灰白质对比度不高。②b=2000s/mm2时,DTI图像质量较好,对比度较佳,能提供更多的扩散信息,更好地反应脑组织内水分子的扩散特性。③b=3000s/mm2时,DTI图像质量较差,对比度最好,但与b=2000s/mm2组差异不显著(P>0.05),而且增加扫描时间。笔者认为扩散梯度因子b=2000s/mm2时,图像综合质量最优,建议常规应用。 Objective To evaluate the change of diffusion tensor ima gi ng (DTI) of normal human brain at different b values. Methods DTI were performe d on 28 healthy adults at b=1000 s/mm2, b=2000 s/mm2 and b=3000 s/mm2 respectively. Diffusion tensors maps, including ADCiso and anis otropic maps, were reconstructed by analysis software provided by Philips Corpor ation. Signal noise ratio (SNR) and contrast between grey matter (GW) and white matter (WM) were measured. Results Significantly increased contrast was revealed on isotropic map and ADCiso map. Significant difference was found between b=200 0 s/mm2 group(or b=3000 s/mm2) and b=1000 s/mm2 group, P< 0.001; while there was no significant difference between b=2000 s/mm2 group and b=3000 s/mm2 group (P >0.05). Conclusion ① The image quality of DTI is the best at b=1000 s/mm2, whi le the contrast between GW and WM is poor. ② Satisfying image quality and cont rast between GW and WM are obtained on DTI at b=2000 s/mm2, in which more diffus ion information is provided. And in this condition, the characteristics of water diffusion in brain tissue can be well displayed.③ There are nice contrast and worse SNR on DTI at b=3000 s/mm2, which has no significant difference with the D TI at b=2000 s/mm2 (P >0.05), and also extends the scan duration. In conclusion, DTI at b=2000s/mm2 may be a routine application due to better SNR and contrast.
出处 《影像诊断与介入放射学》 2004年第3期148-152,共5页 Diagnostic Imaging & Interventional Radiology
关键词 脑组织 磁共振 DTI 扩散张量成像 白质 正常人 人脑 显示 图像质量 Magnetic resonance imaging Diffusion tensor B value
  • 相关文献

参考文献5

  • 1J.C.Tamraz.Y G Comair.et a1.主编 崔世民,张蕾莉,刘梅丽,主泽.脑磁共振局部解剖与功能图谱.北京:人民卫生出版社.2001.29—35,41—48.
  • 2Papadakis NG, Xing D, Houston GC, et al. A study of rotationally invariant and symmetric indices of diffusion anisotropy.Magnetic Resonance Imaging. 1999, 17:881 - 892.
  • 3Shrager RI, Basser PJ. Anisotropically Weighted MRI. Magn Reson Med, 1998, 40:160 - 165.
  • 4Burdette JH, Elster AD, Ricci PE. Acute cerebral in farction:quantification of spin-density and T2 shine - through phenomena on diffusion-weighted MR imsges. Radiology. 1999,212:333 - 339.
  • 5Clark CA, Hedehus M, Moseley ME. In vivo mapping of the fast and slow diffusion tensors in human brain. Magn Roson Meal, 2002, 47:623 - 628.

同被引文献46

引证文献8

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部