期刊文献+

正电子发射断层扫描图像部分容积效应的模拟研究及实验检验 被引量:6

Simulation Study and Experiment Verify of Partial Volume Effect for Positron Emission Tomography
下载PDF
导出
摘要 用模拟实验研究了正电子发射断层扫描(PET)部分容积效应与相关影响因素间的关系。依据形成部分容积效应的理论,由计算机模拟PET各种分辨率情况下各种大小热灶的图像。计算图像的最大恢复系数、平均恢复系数及图像热灶半高宽,并用PET实验进行了检验。结果表明:PET实验的结果与模拟结果一致;当热灶直径以PET分辨率为单位时,图像热灶的最大及平均恢复系数随热灶直径的变化与分辨率无关,且热灶半高宽/分辨率与热灶直径的关系不受分辨率影响。 Partial volume effect (PVE) and their influence factors for positron emission tomography (PET) were investigated with computer simulation and experiments. According to the theory of PVE formation, PET images of the hot lesions with different sizes under various system resolutions were simulated with computer program. The maximum recovery coefficient (RC), the average RC in the region of interest of which the size was the same as the real size of the hot lesion, and the full width at half maximum of the hot lesion on the images were calculated and compared with real experiments results. The results of simulation experiments quite agree with the real experiments. The variation curves of the maximum RC, average RC, and the ratio of the full width at half maximum of the hot lesion to the system resolution versus the diameters of the hot lesion, if the real lesion size is scaled in the system resolution, are independent of the system resolution.
出处 《原子能科学技术》 EI CAS CSCD 2004年第5期467-473,共7页 Atomic Energy Science and Technology
基金 国家"863"基金资助项目(2002AA205081)
关键词 部分容积效应 正电子发射断层扫描 PET 实验检验 关系 图像 影响 恢复系数 平均 计算图 Computer simulation Diagnostic radiography Image processing Medical imaging
  • 相关文献

参考文献7

  • 1Geng Jianhua, Chen Yingmao, Yin Dayi, et al. Noise Components on Positron Emission Tomography Images[J]. Bio-Med Mater Eng,2003,13:181~186.
  • 2Tarantola G,Zito F, Gerundini P.PET Instrumentation and Reconstruction Algorithms in Whole-body Applications[J]. J Nucl Med,2003,44:756~769.
  • 3耿建华,陈盛祖,陈英茂,田嘉禾.正电子图像部分容积效应成因与校正的理论探讨[J].中华核医学杂志,2003,23(5):318-319. 被引量:17
  • 4Frouin V, Comtat C, Reilhac A, et al. Correction of Partial Volume Effect for PET Striatal Imaging: Fast Implementation and Study of Robustness[J]. J Nucl Med, 2002, 43:1 715~1 726.
  • 5Chen CH, Muzic RF Jr, Nelson AD, et al. Simultaneous Recovery of Size and Radioactivity Concentration of Small Spheroids With PET Data [J]. J Nucl Med, 1999, 40:118~130.
  • 6陈英茂,耿建华,田嘉禾,何义杰,陈盛祖.PET显像部分容积效应的实验研究[J].中国医学影像技术,2004,20(1):99-102. 被引量:23
  • 7陈英茂,耿建华,田嘉禾,尹大一,何义杰,陈盛祖.PET系统分辨力及影响因素的实验研究[J].中国医学影像技术,2004,20(5):778-780. 被引量:15

二级参考文献23

  • 1[2]Geworski L, Knoop BO, Cabrejas ML, et al. Recovery correction for quantitation in emission tomography: a feasibility study[J]. Eur J Nucl Med, 2000,27(2):161-169.
  • 2[3]Frouin V, Comtat C, Reilhac A, et al. Correction of partial volume effect for PET striatal imaging: fast implementation and study of robustness[J]. J Nucl Med, 2002,43(12):1715-1726.
  • 3[4]Meltzer CC, Kinahan PE, Greer PJ, et al. Comparative evaluation of MR-based partial volume correction schemes for PET[J]. J Nucl Med,1999, 40(12):2053-2065.
  • 4[5]Chen CH, Muzic RF Jr, Nelson AD, et al. A nonlinear spatially variant object-dependent system model for prediction of partial volume effects and scatter in PET[J]. IEEE Trans Med Imaging,1998,17(2):214-227.
  • 5[6]Chen CH, Muzic RF Jr, Nelson AD, et al. Simultaneous recovery of size and radioactivity concentration of small spheroids with PET data[J]. J Nucl Med,1999,40(1):118-130.
  • 6[9]Hoffman EJ, Huang SC, Phelps ME. Quantification in positron emission computed tomography. 1. Effect of object size[J]. J Comput Assist Tomogr, 1979,3(3):299-308.
  • 7[10]Menda Y, Bushnell DL, Madsen MT, et al. Evaluation of various corrections to the standardized uptake value for diagnosis of pulmonary malignancy[J]. Nucl Med Commun, 2001, 22(10):1077-1081.
  • 8[2]Brix G,Zaers J,Adam LE,et al.Performance evaluation of a whole body PET scanner using the NEMA protocol[J].J Nucl Med,1997,38(10):1614-1623.
  • 9[3]Tarantola G,Zito F,Gerundini P.PET instrumentation and reconstruction algorithms in whole-body applications[J].J Nucl Med,2003,44(5):756-769.
  • 10[4]Wienhard K,Eriksson L,Grootoonk S,et al.Performance evaluation of the positron scanner ECAT EXACT[J].J Comput Assist Tomogr,1992,16(5):804-813.

共引文献35

同被引文献85

  • 1耿建华,陈英茂,陈盛祖,田嘉禾,何义杰,乔士珍.符合线路显像与PET显像中SUV的比较研究[J].中华核医学杂志,2004,24(5):308-309. 被引量:11
  • 2时红伟,陈世平.一种基于现代通信理论的图像质量评价技术[J].中国空间科学技术,2005,25(1):1-6. 被引量:3
  • 3耿建华,陈英茂,陈盛祖,司宏伟,张雯杰,郑容,田嘉禾.双探头符合成像系统的分辨率及其影响因素[J].核电子学与探测技术,2007,27(2):180-183. 被引量:3
  • 4Lenders K,Perani D,Lammertsma A,et al.Cerebral blood flow,blood volume and oxygen utilization[J].Normal values and effect of age.Brain,1990,113:27-47.
  • 5Marchal G,Rioux P,Petit-Taboue M-C,et al.Regional cerebral oxygen consumption,blood flow,and blood volume in healthy human aging[J].Arch Neurol,1992,49:1013-1020.
  • 6Meltzer CC,Cantwell MN,Greer PJ,et al.Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction[J].Nucl Med,2000,41:1842-1848.
  • 7Giovacchini G,Lerner A,Toczek MT,et al.Brain incorporation of 11C-arachidonic acid,boold volume,and blood flow in healthy aging:a study with partial-volume correction[J].Nucl Med,2004,45:1471-1479.
  • 8Frouin V,Comtat C,Reilhac A,et al.Correction of Partial Volume Effect for PET Striatal Imaging:Fast Implementation and Study of Robusmess[J].Nucl Med,2002,43:1715-1726.
  • 9Bencherif B,Stumpf MJ,Links JM,et al.Application of MRI-based partial-volume correction to the analysis of PET images of u-opioid receptors using statistical parametric mapping[J].Nucl Med,2004,45:402-408.
  • 10Quarantelli M,Berkouk K,Prinster A,et al.Integrated software for the analysis of brain PET/SPECT studies with partial-volume-dffect correction[J].Nucl Med,2004,45:192-201.

引证文献6

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部