摘要
目的 制定排石止痛合剂的质量标准。方法 用TLC法鉴别制剂中延胡索、木香、大黄;用HPLC法测定芍药苷的含量。结果 TLC色谱中能明显地检出延胡索、木香、大黄;HPLC法测定,芍药苷在0.8～26.0μg·mL-1线性良好,r=0.999 6(n=6),平均回收率为99.64％,RSD为0.29％。结论 定性、定量方法简便、准确,专属性强,能有效控制排石合剂的质量。
OBJECTIVE To establish the method for quality control of Paishizhitong mixture. METHODS rhizoma corydalis, radix aucklandiae, radix et rhizoma rhei in the mixture was identified by TLC. The content of paeoniflorin was determined by HPLC. RESULTS Rhizoma Corydalis, Radix Aucklandiae, Radix et Rhizoma Rhei could be identified by TLC; with HPLC-U to determine the content of paeoniflorin. The linear range was 0. 8-26. 0μg·mL-1. r=0. 999 6 (n=6) . The average recovery was 99. 64% and the RSD was 0. 29%. CONCLUSIONS The method is sensitive , accurate, simple and the standard can be applied to control the quality of the mixture.
出处
《中南药学》
CAS
2004年第5期293-295,共3页
Central South Pharmacy
