摘要
观察心脏起搏治疗对伴随缓慢性心律失常的急性脑梗塞患者中枢神经功能恢复的影响。选择 1996年 3月至 2 0 0 4年 2月 36例患者 ,其中男 2 4例、女 12例 ,年龄 72 .2 5± 6 .0 8(5 4~ 82 )岁 ,对依次入院的伴随缓慢性心律失常的急性脑梗塞患者在常规脑梗塞治疗的同时置入人工心脏起搏器 (处理组A) ,与单纯常规治疗患者 (对照组B)按1:1序贯配对。所有患者在入院时、治疗 6周及 6个月随访时分别按欧洲神经系统评分 (ESS)标准进行神经系统功能评估 ,配对分析两组神经功能恢复的差别。结果 :治疗前两组ESS无差异 (P >0 .0 5 ) ;A组治疗后 6周、6个月ESS分别较治疗前增加 2 3.6 1± 14 .0 1和 2 8.78± 15 .93(P均 <0 .0 1) ;B组治疗后 6周、6个月ESS无明显改善 (P均 >0 .0 5 ) ;治疗 6周、6个月ESS改善值A组均明显优于B组 (P <0 .0 0 1)。结论 :伴随缓慢性心律失常的急性脑梗塞患者 ,常规治疗并及时接受心脏起搏治疗 ,神经功能的恢复优于未接受心脏起搏治疗者。
To investigate the effects of cardiac pacing on central nervous function recover y of patients with acute cerebral infarction accompanied by bradycardia. From March 1996 to February 2004, 36 hospitalized patients (72.25±6.08 years) with acute cerebral infarction accompanied by bradycardia were coupled 1:1 in order, and ev ery couple were divided into A (conventional therapy plus cardiac pacing) and B (onl y conventional therapy). The nervous system scores (The European stroke scale, ESS ) were evaluated respectively at administration, 6 weeks,and 6 months after therap y. Results: The ESSs in group A and B had no significant difference ( P>0.05 ) . The ESSs in group A increased by 23.61±14.01(P<0.01)at 6 week and by 28 .78±15.93(P<0.01)at 6 month after treatment; while no significant changes of the ESSs in group B at 6 week and 6 month(all P>0.05 ). The increased ESSs in group A at 6 week and 6 month overmatched that in group B (P<0.001). Conclusion:Cardiac pacing benefits to the rehabilitation of centr al nervous functions of patients with acute cerebral infarction accompanied by bradycardia.
出处
《中国心脏起搏与心电生理杂志》
2004年第5期347-349,共3页
Chinese Journal of Cardiac Pacing and Electrophysiology