摘要
目的 :优选三效微型灌肠剂的制备工艺。方法 :以浸膏得率和没食子酸含量为指标成分 ,采用正交试验对三效微型灌肠剂的制备工艺进行优选。结果 :采用水提醇沉法制备。将药材打成粗粉末 ,加入适量的水 ,1h提取1次 ,滤液浓缩至1∶1 41(每1ml相当于含生药1.41g) ,以50%的乙醇沉淀杂质 ,并以适量盐酸调节pH值为5 0。结论 :该工艺合理、简便 ,适合大批量生产。
Objective:To optimize the preparation techniques for the San Xiao micro enemata.Methods:By taking the rate of extractum and the gallic acid content as the indexes components,the preparation techniques were optimized for the San Xiao micro enemata through the orthogonal test.Results:The enemata was prepared by the water-extraction and alcohol-precipitation method.After the crude drugs were smashed into coarse powders,an appropriate amount of water was added and the extraction process was conducted every hour.Then the colature was concentrated to1∶1.41(1ml is equal to1.41g.),and the impurity was precipitated with50%alcohol and a proper amount of hydrochloric acid was added for regulation of pH into5.0.Conclusions:This technique is easy for operation and ideal for mass production.
出处
《广西中医药》
2004年第5期49-52,共4页
Guangxi Journal of Traditional Chinese Medicine
