摘要
目的 :分析总结近年来药物性肝病的情况 ,提高本病的诊断治疗水平。方法 :回顾调查 1994～ 2 0 0 4年各种药物致药物性肝病 4 94例 ,分析统计每年发病例数的变迁及临床情况。结果 :抗结核药、中草药、抗生素、抗肿瘤药、抗甲亢药是主要的损肝药物 ,本病近 10年来每年的发病率在逐年增加 ,平均发病时间 6 3.5 2d ,用药 1个月内发病的占 6 1.34% ,2个月内的占 70 .2 4 % ,无症状者占 4 5 .14 % ,有症状者占 5 4 .86 % ,治疗后总有效率 93.18%。结论 :临床应重视本病 。
Objective: To analyse state of drug-induced liver disease and promote the clinical level on diagnosis and therapy. Methods: Investigate causes, incidence and changes of drug-induced liver during 1994 to 2003 by Investgated 494 cases. Results: Antituberculosis, traditional Chinese medicines, antibiotics, anti-canaer drugs, Antithyroid drugs were the most common drugs for drug-induced liver disease. The incidence of induced-liver disease annually was increaed. The time of drug-induced liver disease average was 63.52 days. The incidence had 61.34% in the first month and 70.24% in the srcond month. The symptomtic patients had 54.86% and Not was 45.14% in 494 cases. The total effect was 93.18% on after treatment. Conclusion:Should attention to drug-induced liver disease and during drugs treatment.physicians monitor liver function.
出处
《中国临床医学》
2004年第4期494-495,共2页
Chinese Journal of Clinical Medicine
关键词
药物性肝病
调查
分类
用药时间
Drug-induced liver disease Injury liver durgs
