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超声引导下射频消融治疗转移性肝癌 被引量:3

ULTRASOUND-GUIDED RADIORFREQUENCY ABLATION OF LIVER METASTASES
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摘要 目的 分析超声引导下射频消融治疗转移性肝癌的近期疗效。方法 对 18例患者共 35个病灶经皮肝穿刺插入可伸缩的多电极射频针进行原位凝固灭活治疗 ,肿瘤最大直径 11.2 cm,最小直径 1.5 cm。结果 观察治疗后的复发和生存情况 ,治疗后 3个月开始随访 ,随访最长时间为 32个月 ,增强 CT提示无强化率 91.6 % ,彩色多普勒提示肿瘤内血流信号消失率 82 % ,治疗后活检提示肿瘤完全坏死率 89% ,4 4 %的患者癌胚抗原明显降低 ,一年生存率 78% ,复发率 15 %。结论 超声引导下经皮穿刺射频消融治疗具有操作简单、创伤小、恢复快、并发症少等优点 。 Objective To analyze the short-term outcomes of radiofrequency (RF) ablation for metastatic liver tumors.Methods RF thermal ablation of a total of thirty-five liver lesions from 18 patients were performed with multiple retractable RF needle electrodes percutaneously, under guidance of ultrasound. The maximum and minimus diameter of lesions were 11.2cm and 1.5cm respectively. The tumor recurrence and the survival rates were investigated.Result The follow-up began after 3 months post-procedure, and the longest duration were 32 months. The hypointense lesions were confirmed in 91.6% lesions with contrast-enhanced CT scan, and disappearance of signals of blood stream were found in 82% lesions with color Doppler ultrasounic detection. Significant reduction of carcinoembryonic antigen (CEA) was present in 44% of cases. The overall one-year survival rate was 78%, the recurrence rate 15%.Conclusion Ultrasound-guided percutaneous RFAis a simple, less invasive treatment option with low complications, which is expected to offer an premising modality for treatment of liver metastases.
出处 《肝胆外科杂志》 2004年第5期350-352,共3页 Journal of Hepatobiliary Surgery
关键词 超声 射频消融 转移性肝癌 ultuasound, Radio-frequency ablatic,liver metastases
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参考文献5

  • 1Rhim H,Dodd Ⅲ GD. Radiofrequency thermal ablation of liver tumors[J]. J Clin Ultrasound, 1999 ;27: 221-229
  • 2Liu JB. Ultrasound-guided radiofrequency ablationoflivertumors [J]. Proceeding of the National Ultrasound Symposium of Chinese Ultrasound Society. Wuhan,China 1999.7-10
  • 3Gerald DD, Michael CS. Minimally invasive treatment of malignant hepatic tumors: at the threshold of a major breakthrough [J]. Radiographics, 2000; 20: 9-27.
  • 4Lirraghi T, Solbiati L, Meloni MF, et al. Treatment of focal liver tumors with percutaneous radio preguency ablation: complications encountered in a multicenter study [J]. Radiology,2003,226:441-451
  • 5Goldberg BB, Liu JB,Merton DA,Rawool NM,Needeman N,Forsberg F. Contrast-enhanced sonography for guidance and evaluation of liver tumor ablation[J]. J Ultrasound Med, 2000;19:S30

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