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瑞芬太尼靶控输注结合丙泊酚用于结肠镜检查的麻醉 被引量:38

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摘要 目的研究瑞芬太尼靶控输注结合丙泊酚用于结肠镜检查的麻醉效果。方法 选择结肠镜检查病人68例,随机均分为瑞芬太尼(A)组与芬太尼(B)组。A组,瑞芬太尼以血浆靶浓度1ng/ml给药;B组单次给芬太尼1 μg/kg。1min后所有病人静注负荷量丙泊酚0.5 mg/kg,继以缓慢间断推注每次10mg,至RamsayⅢ~Ⅳ级。记录诱导、插镜、苏醒及留观时间。记录各时点MAP、HR、SpO2、PETCO2、RR及BIS值。记录术中肢动、呼吸暂停次数。记录病人满意度。结果A组病人的诱导、清醒、留观时间均显著少于B组(P<0.01)。丙泊酚用量A组显著少于B组(P<0.01),术中A组的MAP下降低于B组(P<0.01)。术中肢动A组少于B组,呼吸抑制A组大于B组。病人的满意度A组高于B组。结论静脉靶控输注瑞芬太尼结合丙泊酚镇静是门诊手术麻醉的良好选择,但需加强呼吸监护与管理。
出处 《临床麻醉学杂志》 CAS CSCD 2004年第10期606-607,共2页 Journal of Clinical Anesthesiology
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