摘要
观察云克 ( 99Tc MDP)治疗恶性肿瘤骨转移的临床疗效及不良反应。取云克冻干品 2 0 0mg ,用 2 5 0～ 5 0 0mL生理盐水溶解 ,静脉滴入 3h ,连续 5d为 1个疗程 ;隔 1周或隔 2周重复治疗。 2个疗程以上者统计资料分析。结果云克治疗骨转移癌疼痛的总有效率为 82 % ( 5 5 /67) ;改善活动障碍的有效率为 72 % ( 18/2 5 ) ;止痛维持时间平均1个月 ;无明显不良反应。初步研究结果提示 ,云克是一种治疗恶性肿瘤骨转移的有效药物 ,能有效缓解骨痛、改善活动功能障碍、降低血钙、提高患者生活质量 ;
The objective of this work was to study the clinical effect of 99Tc-MDP on bone metastasis. 99Tc-MDP 200 mg was dissolved in 0.9% NS 250-500 mL and venous drip for 3 hours in 67 patients with bone metastasis for continuous 5 days, then the drip treatment was repeated after one or two weeks for 5 days.The clinical efficacy was observed on pain degree, active efficacy and some other test indices.The results showed the total remission rate of pain was 82%(55/67),and 72%(18/25) of action was improved and average sustainable time in pain remission was about one month. The initial result indicated that 99Tc-MDP could remit the pain in bone metastasis event and improve the physical action as well as the quality of life. Chin J Cancer Prev Treat,2004,11(10):1097-1098
出处
《肿瘤防治杂志》
2004年第10期1097-1098,共2页
China Journal of Cancer Prevention and Treatment
