摘要
目的规范头孢菌素类药物用药行为 ,确保医疗护理安全。方法对接受头孢菌素类药物治疗的患者进行拟用药物过敏试验 ,试敏浓度为 0 .5mg/ml,皮内注射 0 .1ml,2 0min后观察结果 ,皮试结果的判断同青霉素皮试规定。结果 10 2 3例次头孢菌素类药物试敏结果 ,15例次阳性 ,阳性率为 1.4 9%。在使用β 内酰胺类抗生素的 184 8例次间 ,交叉过敏 7例次、非完全交叉过敏 4 3例次 ,头孢菌素类抗生素间交叉过敏 1例次、非交叉过敏 5例次。结论 β 内酰胺类药物间存在着交叉与非交叉过敏反应 ,因此在使用头孢类药物前必须对拟用药物进行试敏 ,防止药物过敏反应。
Objective To standardize the use of cephalosporins antibiotics in order to ensure medical and nursing safety. Method Drug sensitive test were performed for patients administrated cephalosporins antibiotics. The drug concentration for sensitive test was 0.5mg/mL, 0.1mL was used for intradermal injection. The test result was observed and analyzed 20 minutes after test using the same indicator as penicillin. Result Among 1023 cases of patients with cephalosporins sensitive test, 15 cases have positive results, positive rate was 1.49%, among 1848 cases patients using β-Lactam antibiotics, across sensitivty were 7 cases , incomplete across sensitivity were 43 cases, across sensitivity between cephalosporins antibiotics was 1 cases, non across sensitivity were 5 cases. Conclusion There are across and non across sensitivity in β-Lactam antibiotics. Drug sentivity test should be done before administration to prevention drug sensitivity reaction.
出处
《护士进修杂志》
北大核心
2004年第11期971-972,共2页
Journal of Nurses Training
基金
南通市科技局立项项目 (项目编号S30 0 80 )
关键词
头孢菌素
皮肤过敏试验
临床应用
Cephalosporin Intradermal sensitivity test clinical application
