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^(125)IUdR治疗膀胱癌的研究概况 被引量:1

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摘要 12 5I在衰变过程中产生俄歇电子 (Augerelectron) ,进入细胞DNA后可产生显著的细胞毒性 ,1 2 5I-脱氧尿嘧啶核苷 ( 1 2 5I -UdR)是将1 2 5I引入细胞核的有效载体。大量动物和临床实验已经证实 :局部、持续或间隔反复注射或灌注1 2 5I -UdR于肿瘤组织内 ,可产生强烈的肿瘤细胞损伤效应 ,达到治疗肿瘤的目的。由于膀胱自身特点 ,在治疗膀胱癌方面具有独特的易灌注及观察性 ,能高效、选择杀伤肿瘤细胞 ,明显降低膀胱癌复发率 ,故可作为外科手术的辅助治疗手段 ,从而提高膀胱癌患者生存率。
出处 《国外医学(泌尿系统分册)》 2004年第6期770-773,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 膀胱肿瘤
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参考文献10

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同被引文献7

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