摘要
为避免传统金属骨折固定材料应力遮挡效应,采用真空浸渍法制备了新型骨折固定用三维编织碳纤维/环氧(C3D/EP)复合材料,研究了该材料的弯曲、剪切和冲击性能,讨论了其失效方式,通过体外细胞培养法对C3D/EP复合材料的细胞毒性进行了评价.结果表明,与常用金属骨固定材料相比,纤维含量为43%的C3D/EP复合材料弯曲强度已超过不锈钢并接近钛合金,但模量比后二者低得多,与人骨相近;与长纤维复合材料(CL/EP)相比,C3D/EP复合材料破坏时不发生脆性断裂,另外,3T3细胞系和小鼠骨髓基质细胞毒性实验表明,该材料基本没有细胞毒性.上述结果表明该C3D/EP骨折固定复合材料具有良好的应用前景.
In order to avoid the stress shield effect of traditional metal materials,a novel bone fracture fixation material of three-dimensionally braided carbon fiber reinforced epoxy resin(C_(3D)/EP)composites is prepared by vacuum impregnation technique.The mechanical properties of the C_(3D)/EP composites are analyzed.The flexural,shear,impact strengths and flexural modulus of the C_(3D)/EP composites,as well as the long carbon fiber reinforced epoxy resin (C_L/EP) composites are tested.The cytotoxicity of the C_(3D)/EP composites is evaluated with a method of in vitro cell culturing.The results show that the flexural strength of C_(3D)/EP composites with (43%) fibers exceeds stainless steel and approaches Ti-Al-V alloy,moreover,the flexural modulus of C_(3D)/EP composites is much lower than and close to that of the bones.In contrast to the C_L/EP composites,the C_(3D)/EP composites exhibit higher impact strength and ductile fracture mode.It′s also observed that the 3T3 cells and mouse marrow stromal cells grow well on the surface of C_(3D)/EP composites, which clearly demonstrates that the C_(3D)/EP composites have no cytotoxicity and are possible to be used for fracture fixation in the future.
出处
《天津大学学报（自然科学与工程技术版）》
EI
CAS
CSCD
北大核心
2004年第11期1009-1013,共5页
Journal of Tianjin University：Science and Technology
基金
天津市重大科技攻关基金资助项目(013111711).
关键词
复合材料
三维编织
力学性能
细胞毒性
骨折固定
composites
three-dimensionally braid
mechanical properties
cytotoxicity
bone fracture fixation
