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系统性硬化症肺部病变的临床特征及病理特点 被引量:3

Clinicopathological Studies of Pulmonary Involvement of Patients with Systemic Sclerosis
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摘要 目的 :了解系统性硬化症 (SSc)患者肺部病变的临床特征及病理特点。方法 :对确诊的 6 8例 SSc进行回顾性临床分析。结果 :5 7例 (83.8% )有程度不同的胸部 X线异常 ,4 4例 (6 4 .7% )有明显肺纤维化征象 ,5例无肺纤维化征象而以肺动脉高压和 (或 )心衰为突出表现。14例死亡主要原因为呼吸衰竭及心功能不全。6 8例中有 6例伴发恶性肿瘤。结论 :SSc肺损害发生率高 ,肺纤维化和肺功能不全进程与患者预后密切相关。 Objective:To assess the incidence of pulmonary lesions of patients with systemic sclerosis(SSc) as well as its clinical and pathological changes.Methods:The pulmonary lesions was studied clinicopathologically in 68 patients who were compatible with the diagnosis of SSc.Results:There were 57 (83.8%) cases with the abnormal change of different extension in the roentgen of chest, 44 (64.7%) with significant pulmonary fibrosis,six with the malignant tumor, five without pulmonary fibrosis but with marked pulmonary hypertension and/or cardiac failure,and 14 died of the distinct cardiopulmonary involvement among them.Conclusion:Morbidity of pulmonary lesions of patients with SSc is significantly increased.The course of pulmonary fibrosis and pulmonary insufficiency of patients with SSc is closely related with their prognosis.
出处 《中国误诊学杂志》 CAS 2004年第4期481-484,共4页 Chinese Journal of Misdiagnostics
关键词 硬皮病 系统性/病理学 肺纤维化/病理学 Scleroderma,systemic/pathology Pulmonary fibrosis/pathology
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参考文献8

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二级参考文献5

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