摘要
目的 :探讨糖尿病患者膀胱功能变化及其机制。方法 :将 70例糖尿病患者按照病程分为早期组和进展期组 ,分别对其初尿意的膀胱容量、最大膀胱容量、最大自由尿流率、最大尿流时的逼尿肌压力 (PQmax)、剩余尿量进行分析。结果 :早期组糖尿病患者产生初尿意的膀胱容量增大至 (15 1.6 7± 2 4 .0 7)ml,进展期糖尿病患者初尿意的膀胱容量进一步增大至 (2 6 8.16± 13.90 )ml,最大膀胱容量增大至 (5 92 .97± 2 5 2 .5 1)ml,最大自由尿流率降低至 (8.6 1± 2 .0 4 )ml/min ,PQmax降低 (3.2 5± 1.94 )kPa ,剩余尿量增加至 (16 9.0 3± 137.2 5 )ml。结论 :早期糖尿病患者膀胱感觉减退可能是逼尿肌兴奋性降低的缘故 ;进展期糖尿病患者的一系列尿动力学改变 ,可能是在逼尿肌兴奋性改变的基础上出现逼尿肌收缩力降低的结果。
Objective:To observe the changes of bladder in diabetes mellitus patients.Methods:Analyze the urodynamic finding of 70 diabetes mellitus patients retrospectively.These patients were divided into early stage groups and progression stage group by course of disease. Selected the volume of first bladder sensation, maximum detrusor voiding pressure , maximum flow rate, residual urine volume and bladder capacity as parameter.Results:At early stage group the volume of first bladder sensation was ( 151.67± 24.07)ml. At progression stage it was ( 268.16± 13.90)ml. and bladder capacity was ( 592.97± 252.51)ml. The maximum flow rate was ( 8.61± 2.04)ml/min. PQ max was ( 33.16± 19.81)cmH 2O. The residual urine volume was ( 169.03± 137.25)ml. They are all abnormal.Conclusions:At the early stage the reason of reduction in the bladder sensation may be the excitability depression, which leads to threshold of the tension significantly higher than the control. At the progression stage the bladder sensation reduced too. and the urodynamic finding such as the bladder capacity / maximum flow rate / residual urine volume had changed .The reason may be the contraction decreased after the excitability depressed.
出处
《临床泌尿外科杂志》
2004年第11期646-648,共3页
Journal of Clinical Urology
基金
山西省归国留学人员基金资助 (No :0 110 )
山西省自然科学基金 (No :2 0 0 2 1112 )
关键词
尿动力学
膀胱疾病
糖尿病
Urodynamic
Bladder disease
Diabetes mellitus
