摘要
建立了HPLC法测定清热消炎片中大黄酚的含量。采用C18色谱柱,流动相为甲醇-0.1%磷酸(90∶10),流速0.8ml/min,检测波长254nm。大黄酚在0.048～0.48mg时线性关系良好(r=0.9995)。平均回收率为100.7%(RSD=0.4%)。
A HPLC method for the determination of chrysophanol in Qingre Xiaoyan tablets was established. A C18column was used with the mobile phase of methanol-0.1% phosphoric acid (90∶10) at the detection wavelength of254nm. The flow rate was 0.8ml/min.The calibration curve was linear in the range of 0.048～0.48mg (r=0.9995). Theaverage recovery was 100.7% (RSD=0.4%).
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2004年第8期490-491,共2页
Chinese Journal of Pharmaceuticals
