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Lugol液染色诊断早期食管癌的临床价值 被引量:13

Clinical value of detecting early esophageal cancer with Lugol's staining
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摘要 目的 评价内镜下Lugol溶液染色诊断早期食管癌的应用价值。方法 对 111例食管表浅性病变行 2 %Lugol液染色 ,同时行活组织病理检查。结果 正常染色 4例 ,浅染色 6 8例 ,不染色2 8例 ,过度染色 11例。病理结果提示正常染色及过度染色组中未发现癌变或癌前病变 ,浅染色组 6 8例中发现重度异型增生 3例、癌变 (原位癌 ) 1例 ,不染色组 2 8例中发现鳞癌 17例 (原位癌 7例 )、重度异型增生 5例。结论 食管病变Lugol液染色呈不染或浅染色的病例 ,往往提示癌变或癌前病变 ,结合活检可以提高早期食管癌的诊断率。 Objective To evaluate the role of Lugol’s s taining in detecting early esophageal cancer.Methods 2% Lugol’s solution was adopted to stain esophageal m ucosa in 111 cases with esophageal superficial lesions. And multiple biopsies we re taken for pathological study.Results Among the 111 cases with Lugol’s staining, the results in normal, light, deep and non-stained were 4, 68,11 and 28 cases respectively . Pathology result: no cases of esophageal cancer or cell dysplasia in normal an d deep stained groups, 3 cases of severe dysplasia and 1 case of canceration in light stained group, 17 cases of esophageal squamous cell carcinoma and 5 cases of severe dysplasia in un-stained group.Conclusion The cancerous and precancerous lesions are liable to occur in cases with non- and light Lugol’s staining groups. The rate of detec ting early esophageal cancer increased when Lugol’s staining and biopsy are use d in combination.
出处 《中华消化内镜杂志》 2004年第4期245-247,共3页 Chinese Journal of Digestive Endoscopy
关键词 Lugol液染色 诊断 早期食管癌 内窥镜检查 Esophageal neoplasms Lugol’s solution Stain ing Endoscopy
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