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肌注丙种球蛋白治疗特发性血小板减少性紫癜

The Treatment of Idiopathic Thmbocytopenic purpura with Intramuscular Injection of Human Immunoglobulin
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摘要 目的探求治疗小儿特发性血小板减少性紫癜的新方法。方法87例11个月~13岁的本科住院患儿随机分为治疗组:57例,对照组:30例,治疗组应用国产人血丙种球蛋白注射液,<2岁300mg/d,3~6岁600mg/d,>7岁600~1200mg/d,肌肉注射,1~2次/d,疗程5~7天。结果治疗组血小板计数达到正常、出血症状消失所需时间较对照组明显缩短(P<0.01)。结论采用肌肉注射给药方法同样能达到静脉输注的疗效,且具有剂量小、费用少、安全性高、不良反应少等优点,尤其值得在基层医院推广使用。 Objective To investigate the new therapy for Idiopathic thrombocytopenic purpura (ITP). Methods 87 patients aged from 11 month to 13 years were randomly divided into a treatment group (57 cases) and a control group (30 cases). The treatment group was administrated with Hunan immunoglobulin injection. <2y 300mg/d, 3-6y 600mg/d. >600-1200/d intramuscularly injected, once or twice a day, 5-7days being a coarse of treatment. Result The recovery time of platelet counts and disappearance of hemorrhage in the treatment group was significantly shorter than that in the control group (p<0.01), Conclusion ITP treated with intramuscular injection of human immunoglobulin acquired same curative effects as intravenous injection. Furthermore, the advantages of the new therapy are smaller dose, less costs, insignificant side effects and high safety. It is recommend popularizing in basic-level hospital.
出处 《中国病案》 2004年第9期47-48,共2页 Chinese Medical Record
关键词 丙种球蛋白 药物治疗 特发性血小板减少性紫癜 肌肉注射 intramuscularly injected human immunoglobulin purpura thromboey topenic
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