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Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT 被引量:8

Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT
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摘要 AIM: To work out an indMdualized lipiodol dose in transcabheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.METHODS: One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT. Patterns of blood supply of HCC were divided into sufficient blood supply, poor blood supply, mixed blood supply and arteriovenous (A-V) shunt. The dose of ultrafluid lipiodol was determined by diameter and blood supply type of HCC. Patients were divided into two groups (50 cases each): lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor.RESULTS: The confirmation and effective rates were 82%,84% in the first group and 36%, 46% in the second group (P<0.01).CONCLUSION: A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging. AIM:To work out an individualized lipiodol dose in transcatheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT. METHODS:One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT.Patterns of blood supply of HCC were divided into sufficient blood supply,poor blood supply,mixed blood supply and arteriovenous (A-V) shunt.The dose of ultra- fluid lipiodol was determined by diameter and blood supply type of HCC.Patients were divided into two groups (50 cases each):lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor. RESULTS:The confirmation and effective rates were 82%, 84% in the first group and 36%,46% in the second group (P<0.01). CONCLUSION:A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging.
机构地区 DepartmentofRadiology
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第18期2753-2755,共3页 世界胃肠病学杂志(英文版)
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  • 1[1]Nakao N, Uchida H, Kamino K, Nishimura Y, Ohishi H, Takayasu Y, Miura K. Determination of the optimum dose level of lipiodol in transcatheter arterial embolization of primary hepatocellular carcinoma based on retrospective multivariate analysis. Cardiovasc Intervent Radiol 1994; 17:76-80
  • 2[2]Matsuo N, Uchida H, Sakaguchi H, Nishimine K, Nishimura Y, Hirohashi S, Ohishi H. Optimal lipiodol volume in transcatheter arterial chemoembolotherapy for hepatocellular carcinoma: study based on lipiodol accumulation patterns and histopathologic findings. Semin Oncol 1997; 24(2 Suppl 6): 61-70
  • 3[3]Katyal S, Oliver JH, Peterson MS, Chang PJ, Baron RL, Carr BI.Prognostic significance of arterial phase CT for prediction of response to transcatheter arterial chemoembolization in unresectable hepatocellular carcinoma: a retrospective analysis. Am J Roentgenol 2000; 175:1665-1672
  • 4[4]Vogl TJ, Trapp M, Schroeder H, Mack M, Schuster A, SchmittJ, Neuhaus P, Felix R. Transarterial chemoembolization for hepatocellular carcinoma: volumetric and morphologic CT cri teria for assessment of prognosis and therapeutic success-results from a liver transplantation center. Radiology 2000; 214:349-357
  • 5[5]Chung JW, Park JH, Im JG, Han JK, Han MC. Pulmonary oil embolism after transcatheter oily chemoembolization of hepa tocellular carcinoma. Radiology 1993; 187:689-693

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