摘要
目的探讨含碘食物对Graves病患者摄取99mTc与131I的影响。方法选择曾食含碘食物的Graves病患者20例,在禁食含碘食物前后分两次进行摄131I试验与甲状腺99mTc显像,前者测定3、24 h摄131I率,后者计算摄锝指数(TI)及估算甲状腺质量(TW)。采用Wilcoxon 符号秩和检验对数据进行对比分析。结果20例患者禁止含碘食物前后的摄131I率显著不同,所有患者禁食含碘食物后3和24 h摄131I率均显著增高。TI 2例未变、2例增高、16例降低;TM18例减小、2例增大。较未禁食含碘食物的首次检测,两者均有显著性变化。结论含碘食物对甲状腺摄取Na99mTcO4的影响与Na131I显著不同,含碘食物100%减低甲状腺131I的摄取而90%锝摄取增高。
Objective To investigate the changes in 99mTc and 131I uptake in patients with Grave's disease after intake of iodine-containing food. Methods The 3-hour and 24-hour radioactive iodine uptake (RAIU) and 99mTc uptake ratio (TI) were measured and the thyroid weight (TW) was estimated in 20 patients with Graves' disease both before and after restraint of iodine-containing diet. Results Significant difference was found in RAIU and TI in patients after restraint of iodine-rich diet (Z=3.920, P=0.000 for 3-hour RAIU and Z=3.920, P=0.000 for 24-hour RAIU; Z=2.199, P=0.028 for TI and Z=3.920, P=0.000 for TW estimated from 99mTc images). The tendency in such changes was significantly different (Z=4.066, P=0.000 for RAIU and TI; Z=4.243, P=0.000 for RAIU and TW). After restraint of iodine-rich food, RAIU of 3-hour and 24-hour increased in all the patients, and TI decreased in 16, remained the same level in 2 and increased in 2 patients; TW decreased in 18 and increased in 2 patients. Conclusion Iodine-containing food has different effects on thyroid 131I and 99mTc uptakes, which decreases 131I uptake in all the patients and increases 99mTc in 90% of them.
出处
《第一军医大学学报》
CSCD
北大核心
2004年第11期1292-1294,共3页
Journal of First Military Medical University
