摘要
目的 :探讨超微粉碎对穿心莲药材中有效成分溶出率的影响。方法 :用高效液相色谱法 (highperformanceliquidchro matography ,HPLC)测定穿心莲超微粉与药材 12 0目细粉中穿心莲内酯及脱水穿心莲内酯的溶出率。 结果 :超微粉药材中穿心莲内酯及脱水穿心莲内酯的溶出率明显增加。结论 :超微粉碎可显著提高穿心莲药材中有效成分的溶出率。
Objective: To investigate the effects of ultra-fine powder technique on dissolution rates of the components in Andrographis paniculata. Methods: High performance liquid chromatography was employed to determine the concentration of andrographolide and dehydroandrographolide in common powdered or ultra-fine powdered Andrographis paniculata. Results: The dissolution rates of andrographolide and dehydroandrographolide in ultra-fine powdered Andrographis paniculata were higher than those of the general powder. Conclusion: Ultra-fine powder technique promotes the dissolution rates of andrographolide and dehydroandrographolide.
出处
《中西医结合学报》
CAS
2004年第6期456-458,共3页
Journal of Chinese Integrative Medicine
