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凋亡基因与DNA疫苗 被引量:1

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摘要 细胞凋亡产生的凋亡小体可以有效的将携带的抗原定位于抗原提呈细胞 (APC )中 ,因此 ,使用经过改造的致凋亡基因与抗原基因共转染宿主细胞 ,诱导宿主细胞凋亡发生 ,可有效地促进DNA疫苗的免疫原性。而使用抗凋亡基因与抗原基因特异性的共转染抗原提呈细胞 ,也被发现具有重要的免疫辅助作用。
作者 刘浩 姜广水
出处 《现代免疫学》 CAS CSCD 北大核心 2004年第6期520-522,共3页 Current Immunology
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