摘要
目的 研究恶黑的临床病理特点、组织学变异型及鉴别诊断。方法 应用HE染色、免疫组化标记对 130例恶黑形态学进行观察、分析临床资料 ,并划分组织学变异型。结果 根据病理形态学发现及免疫组化标记 ,130例恶黑组织学变异被分为上皮样型、肉瘤样型、癌肉瘤样型、促结缔组织增生型、小细胞型、血管周细胞样型、假腺样型、浆细胞样型、横纹肌样型、巨细胞样型、印戒细胞型、透明细胞型、气球样细胞型及炎性MFH样型。结论 恶黑的组织病理结构和形态变异复杂 ,细胞类型多 ,少色素、无色素及核仁模糊占大多数 ,有不同的病理类型 ,有时诊断很困难 ,应特别注意与多种类型肿瘤相鉴别。
Purpose To study clinicopathologic features, histopathologic variants and differential diagnosis in malignant melanomas. Methods Pathological changes of 130 cases of malignant melanoma were studied with HE staining and immunohistochemistry, and their clinical data were analysis. In addition, types of histopathologic variation were divided. Results According to pathologic findings and immunohistochemical staining, 130 cases of malignant melanoma were classified into epithelioid type,sarcomatoid type,carcinosarcomatoid type,desmoplastic type, small cell type,hemanqiopericytomatous type, pseudoglandular type,plasmacytoid type,rhabdoid type, giant cell type, signet-ring cell type ,clear cell type, balloon cell type and inflammatory MFH-like type. Conclusions Histopathologic structures and morphological variation are very complex in malignant melanoma. There are different histopathologic subtypes, and the diagnosis is very difficult at time. It should be paid more attention to make the differential diagnosis of different subtype of the tumor.
出处
《临床与实验病理学杂志》
CAS
CSCD
2004年第5期588-591,共4页
Chinese Journal of Clinical and Experimental Pathology
