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四君子汤治疗脾气虚型胃肠病SOD、MDA变化的研究 被引量:2

Study on SOD and MDA Changes in Patients with Spleen-QiDeficiency type Stomach-intestine Disease Treated with SiJunZi Decoction (四君子汤 )
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摘要 用四君子汤治疗60例脾气虚型胃肠病患者,观察治疗前后血清总超氧化物歧化酶(SOD)、丙二醛(MDA)值,并与正常对照组比较。脾虚患者SOD低于对照组(P<0.01),而MDA偏高(P<0.01),治疗后与对照组无显著差异(P>0.05)。提示:脾虚患者自由基清除能力下降,脂质过氧化反应增强,四君子汤能逆转此病理过程。 n the study, we used SiJunZi Decoction to treat 60 patients with Spleen-Qi Deficiency (SQD) type stomach-intes-tine disease. we observed the total SOD and MDA level in serum before and after treatment. and compared them withnormal control group. The results showed that the SOD of SOD type cases before treatment was very lower than control group(P>O. 01 ) and the MDA was very higher (P<0. 01 ). The difference in the level of SOD and MDA betweenbefore and after treatment was very significant (P<0. 01 ). This study showed that in patients with SOD type stomachintestine disease. the power of cleaning free radical and LPO was low. SiJunZi Decoction can clean free radical andLPO of the body. It is one of the mechanisms of SiJunZi Decoction to invigorate Spleen-Qi.
出处 《中药药理与临床》 CAS CSCD 1995年第1期45-46,共2页 Pharmacology and Clinics of Chinese Materia Medica
关键词 四君子汤 药物治疗 脾气虚型 胃肠病 SOD MDA 超氧化物歧化酶 丙二醛 Spleen-Qi Deficiency SOD. MDA Stomach-intestine disease SiJunZi Decoction
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  • 1沈自尹,王文健.中医虚证辨证参考标准[J].临床荟萃,1987(4):189-189. 被引量:120
  • 2陈英洋,李金炎,黄福鹏,陈民生,陈国熙.用原子吸收光谱法测定人血清中Zn、Cu、Ca、Mg的方法[J]福建医学院学报,1984(02).
  • 3朱海年.微量元素与健康[M]北京大学出版社,1989.

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