摘要
本文采用301医院内皮素-1放射免疫分析试剂,建立了测定正常肾皮质、肾动脉、肾静脉、腹主动脉中的内皮素-1(ET-1)样免疫活性物质的方法。测定结果表明肾皮质ET-1含量为1453.13±117.60pg/g蛋白,肾动脉为988.37±37.18、肾静脉为250.31±7.25、腹主动脉为255.72±6.18pg/g蛋白,以肾皮质含量最高,后二者含量相近,非常显著的低于肾皮质和肾动脉ET-1样免疫活性物质。这种方法的建立和提供ET-1的数据,为研究ET-1含量变化与肾脏疾病的关系及发病机理有其重要意义。
We measured endothelin-1 (ET-1) levels in the renal cortex(RC),renal artery (RA), renal vein (RV) and abdominal aorta(AA) by radioimmunoassay. The results showed that the ET-1 levels in RC and RA (1453.13±117.60,988.37±37.18 pg/g protein)were significantly higher than those in RV and AA (250.31±7.25, 255.72±6.18pg/g protein, respectively). The establishment of this method and the given data of ET-1 may be of a great significance in studying the relation between ET-1 changes and the renal diseases and their pathogenicity.
出处
《放射免疫学杂志》
CAS
1995年第6期342-343,共2页
Journal of Radioimmanology
