摘要
目的观察沙美特罗替卡松干粉荆吸入治疗儿童哮喘的效果。方法应用沙美特罗替卡松干粉剂吸入治疗4-14岁非急性发作期中、重度哮喘140例,与对照组应用氟替卡松吸入治疗哮喘106例作比较,同时监测肺功能结果治疗组和对照组总有效率分别为99.3％、99.1％,显效率分别为63.7％、56.6％。两组治疗4个月后肺功能第1秒钟用力呼气容积(FEV1)、呼气50％用力肺活量时流速(FEF50%)、最大呼气峰流速(PEF)治疗前相比,均有显著提高(P均<0.01)。结论 应用沙美特罗替卡松干粉刺治疗哮喘具有显著疗效,不良反应少,安全性高。并具有携带、吸药方便,病人易接受,依从性高等优点。
Objective To observe the effects of asthmatic children treated by inhaled salmeterol xinafoate and fluticasone propi-onate powder. Methods One hundred and fourty cases of moderate and severe asthmatic children were treated in non- acute period aged from 4 to 14 years by inhaling salmeterol xinafoate and fluticasone propionate powder, compared with control group treated by flu-ticasone propionate in 106 cases, and the pulmonary function was monitored simultaneously. Results The total effective rate of the treatment group and control group were 99. 3 % , 99. 1 % , respectively.The pulmonary function indexes such as the first one second expiration volume(FEV1), flow velocity of 50 % expiration vital capacity(FEF50%), peak expiration velocity(PEF1) after being treated 4 months was improved significantly compared with those before treatment.The difference between them was statistically significant (P<0.01).Conclusions It is significantly effective, safety,and convenient in inhalation with little side- effects in treatment of asth-matic children by inhaling salmeterol xinafoate and fluticasone propionate powder.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2004年第12期1084-1085,共2页
Journal of Applied Clinical Pediatrics
关键词
哮喘
儿童
吸入
氟替卡松
沙美特罗
asthma
children
inhalation
fluticasone
salmeterol
