摘要
目的 探讨鼻咽非霍奇金淋巴瘤的发病率、疗效及预后。方法 回顾分析鼻咽非霍奇金淋巴瘤 12例的临床资料。结果 本病占恶性淋巴瘤的 3 43 % ,占结外淋巴瘤的 12 9% ,高度恶性占 75 % (9/12 ) ,T细胞占 66 7% (8/12 )。临床表现为鼻塞、鼻腔恶臭异味、鼻涕带血、发热。全部误诊。CR 9例 ,PR 2例 ,PD 1例 ,有效率 (CR +PR)为 91 7% (11/12 )。 2、5年生存率分别为 77 8%、71 4%。结论 鼻咽非霍奇金淋巴瘤临床少见 ,极易误诊。本病疗效较好 ,但高度恶性、T细胞型并伴有发热症状者预后差。
Objective To study the incidence rate, therapeutic effect and prognosis of nasopharyngeal lymphoma (NPL). Methods Retrospective analysis was made for 12 cases with NPL. Results NPL was present in 3.43% of the malignant lymphoma, and 12.9% of extra_nodal lymphoma, high grade in 75%(9/12) and T cell tumor in 66.7%(8/12). Clinical situation of NPL was nasal obstruction, foul smell in nasal cavity, nasal hemorrhage and febrile. The misdiagnostic rate was 100%. The overall response rate (CR+PR) was 91.7%(11/12), with CR 9 cases, PR 2 cases and PD 1 case. The 2_year , 5_year survival rates were 77.8% and 71.4%. Conclusions NPL was seldom present and was often misdiagosed. Therapeutic effect was satisfying. The predisposed factors were a high grade. The prognosis of T cell tumour and febrile was poor.
出处
《河南肿瘤学杂志》
2004年第6期428-429,共2页
Henan Journal of Oncology
