期刊文献+

CD_(44V6)在子宫内膜异位症中的表达及意义 被引量:1

Expression of CD_(44V6) in Human Endometriosis
下载PDF
导出
摘要 目的 检测CD44V6在子宫内膜异位症在位、异位内膜与正常内膜中的表达 ,研究CD44V6在子宫内膜异位症发病中的作用。方法 采用免疫组化方法对 2 0例卵巢子宫内膜异位囊肿在位内膜、异位内膜与 15例正常子宫内膜中CD44V6的表达进行检测。结果 CD44V6在卵巢子宫内膜异位囊肿异位内膜中的表达显著高于同期在位内膜与正常内膜的表达 (P <0 .0 1) ,在位内膜与正常子宫内膜中CD44V6表达无显著性差异 (P >0 .0 5 )。 Objective The aim of this study is to evaluate CD 44V6 expression in endometriotic and eutopic endometrium in women with endometriosis and normal endometrium. Methods CD 44V6 expression was examined in endometriotic and eutopic endometrium (n=20) and normal endometrium (n=15) with immunohistorheonistry. Results Increased expression of CD 44V6 in endometriotic was found as compared with eutopic and normal endometrium (P<0.01), the CD 44V6 expression was similar in the last two groups(P>0.05).Conclusion Our results suggested that CD 44V6 could be involved in the development of endometriotic lessions.
作者 高慧 张向宁
出处 《医学新知》 CAS 2004年第4期233-234,F004,共3页 New Medicine
关键词 CD44V6 子宫内膜异位症 表达 免疫组化 CD44V6 Endometriosis Immunohistrochemistry
  • 相关文献

参考文献6

  • 1Srobel t, Swanson L, Cannistra S A. In vivo inhibition of CD44 limits intra-abdominal spread of a human ovarian cancer xenograft in nude mice: a novel for CD44 in the process of pertoneal implantation. Cancer Res, 1997,57(1):1228
  • 2Humphery P A, Wong A J, Vogelstein B, et al. Amplification and expression of EGFR in human glioma xenografts. Cancerres, 1998,48(3):2231
  • 3Sy Ms, Liu D, Schiavone R, et al. Interactions between CD44 and hy aluronic acid: their role in tumor growth and metastasis. Curr Top Microbiol Immunol, 1996,213(pt 3):129
  • 4Poncelet C, Leblanc M, Walker-Combrouze F, et al. Expression of cadherins and CD44 informs in human endometrium and peritoneal endometriosis. Actaobstet Gynecol Scand, 2002, 81(3):195
  • 5Seiter S, Arch R, Reber S, et al. Prevention of tumor metastasis formation by anti-variant CD44. J Exp Med, 1993, 177(2):443
  • 6Zawadzki V, Pershcl A, Rosel M, et al. Blockade of metastasis formation by CD44-receptor globulin. In J Cancer, 1998,75(6):919

同被引文献1

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部