摘要
目的 :观察几种治疗慢性肾衰常用中药对小肠清除肌酐的影响。方法 :钳夹兔双肾动脉 ,静脉注射肌酐。造瘘用导浊解毒、活血化瘀和补气固本的中药做小肠透析。结果 :1 .枳壳、党参组的肠粘膜肌酐清除率分别为 1 .1 82和 1 .0 0 1 ml.min-1,与对照组 0 .2 91 ml.min-1差异有显著性 ( P<0 .0 0 5)。2 .大黄等其他组对小肠肌酐的清除率与对照组差异无显著性 ( P>0 .0 5)。结论 :导浊解毒、活血化瘀类中药对清除肌酐作用不大 ,行气补气的枳壳、党参液可促进小肠清除肌酐 ,值得进一步研究。
Objective:To investigate the effect of various Chinese herbal medicines on the clearance of creatinine thought small intestine. Method:We used the renal\|artery\|ligated rabbits as the model. After the intravenous administration of creatinine thought ear vein,we had fistulas in small intestine and carried out intestinal dialysis. Result: 1.The clearance of creatinine in treated groups with bitter orange Immature and Dangshen were 1.182 and 1.001 ml·min -1 . They were higher than that in the control group with normal saline solution (P<0 5). 2.The clearance of creatinine in other treated groups with Danshen Root,Rhubarb,Licorice Root,Oyster shell,Glafrous Greenbrier Rhizome were higher than that in the control group. But there was no significant difference (P>0 05). Conclusion:Drugs for Qi\|promoting and Replenishing could promote the clearance of creatinine through small intestinte,but drugs for clearing Qi\,promoting blood circulation and removing blood stasis were of no significant effect.
出处
《中国中医基础医学杂志》
CAS
CSCD
2000年第9期33-35,共3页
JOURNAL OF BASIC CHINESE MEDICINE
关键词
中药
小肠
肌酐
透析
慢性肾衰
Chinese herbal medicines
Intestine,Small
dialysis
Creatinine
Rabbits
Renal failure
