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血清降钙素原检测对院内深部真菌感染诊断价值的探讨 被引量:23

Diagnostic Value of Serum Procalcitonin for Nosocomial Deep Mycotic Infection in Critically ill Patients
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摘要 目的 :探讨血清降钙素原 (PCT)检测诊断危重病患者院内深部真菌感染 (IMI)的价值。方法 :回顾性分析重症监护病房内 5 6例临床资料 ,并与健康组 15例对照。结果 :IMI组较健康对照组血清PCT水平明显升高 (P <0 .0 1)。不同感染部位 ,以血液真菌感染者PCT水平最高 (P <0 .0 1)。但PCT不能鉴别不同真菌菌株。结论 :PCT可作为危重病患者院内IMI有价值的诊断指标。 Objective:To evaluate the diagnostic value of procalcitonin (PCT) in critically ill patients with nosocomial invasive mycotic infection (IMI). Methods: 56 critically ill patients with IMI in intensive care unit were retrospectively analyzed. Results: The PCT levels of patients with IMI were significantly higher than those of control group (P<0.01). The PCT levels of patients with fungemia was the highest among the different locations of mycotic infection (P<0.01). PCT was unable to differentiate different fungal strains. Conclusion: The measurement of PCT might be used as a valuable index in diagnosis of nosocomial deep mycotic infection in critically ill patients.
出处 《内科急危重症杂志》 2004年第4期203-204,共2页 Journal of Critical Care In Internal Medicine
关键词 降钙素原 深部真菌感染 院内感染 危重病 Procalcitonin Invasive mycotic infection Nosocomial infection Critical illness
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  • 1Shimetani N, Shimetani K, Mori M. Levels of three inflammation markers, C-reactive protein, serum amyloid A protein and procalcitonin, in the serum and cerebrospinal fluid of patients with meningitis. Scand J Clin Lab Invest,2001,61:567.
  • 2Brandt ME, Warnock DW. Epidemiology, clinical manifestations,and therapy of infections caused by dematiaceous fungi . J Chemother, 2003, 15(Suppl 2): 36.
  • 3Micharl M Procalcitonin (PCT): A new , innovative infection parameter. New york :Ge org thieme verlag stuttgart , 2000,7-8;15-26.
  • 4Nosari A, Oreste P, Cairoli R, et al. Invasive aspergillosis in haematological malignancies: clinical findings and management for intensive chemotherapy completion Am J Hematol, 2001, 68: 231.
  • 5Bayer L, Schontube M, Dorffel W. C-reactive protein, Il-6 and procalcitonin as infection parameters in children with oncologic diseases. Klin Padiatr, 2000, 212: 326.

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